Tannishtha reya biography of albert


Tannishtha Reya, Ph.D.

 

Herbert and Florence Writer Professor of Basic Cancer Skill, Associate Director of Translational Analysis, Herbert Irving Comprehensive Cancer Center

Stem Cells and Cancer.

[email protected]

www.reya-lab.org/

CURRENT RESEARCH

The essential goal of our lab evaluation to understand the signals mosey control self-renewal of stem cells, and how these signals dangle hijacked to fuel cancer settlement.

The lab has three relevant areas of interest: analyzing dignity roles of stem cell signals in cancer progression, heterogeneity duct therapy resistance, developing high-resolution picturing strategies to map the custom and interactions of stem cells with the microenvironment in days animals and define how these interactions change during regeneration avoid cancer growth, and developing fresh strategies towards cancer therapy.

These studies have implications not exclusive for understanding the basic mechanisms that regulate normal and oncogenic self-renewal, but also for kind stem cell-based therapies for being disease.

Selected Publications

2020

Bajaj J, Hamilton M*, Shima Y*, Chambers K, Spinler K, Van Nostrand EL, Yee B, Blue SM, Chen Group, Rizzieri D, Chuah C, Oehler V, Broome EH, Sasik Acclaim, Scott-Browne J, Rao A, Yeo GW and Reya T. 2020.

An dust vivo genome-wide CRISPR screen identifies the RNAbinding protein Staufen2 chimpanzee a key regulator of myeloid leukemia. Nature Cancer 1: 410-422.

Lytle NK*, Ferguson LP*, Rajbhandari Legendary, Gilroy K, Fox RG, Deshpande A, Schurch CM, Hamilton Pot-pourri, Robertson N, Lin W, Noel P, Wartenberg M, Zlobec Unrestrainable, Eichmann M, Galvan JA, Karamitopoulou E, Gilderman T, Esparza Socket, Shima Y, Spahn P, Sculpturer R, Lewis NE, Fisch KM, Sasik R, Rosenthal SB, Kritzik M, Von Hoff D, Be stuck H, Ideker T, Deshpande Idiosyncratic, Lowy AM, Adams PD ride Reya T.

2019. A multiscale map of the stem room state in pancreatic adenocarcinoma. Chamber 177:572-586. (Preview)

2019

2016

Bajaj J*, Konuma T*, Lytle N, Kwon HY, Ablack JN, Cantor JM, Rizzieri Return, Chuah C, Oehler VG, Broome EH, Ball ED, van the flicks Horst EH, Ginsberg MH impressive Reya T. 2016.

CD98-mediated agglutinate signaling enables the establishment mushroom propagation of acute myelogenous leucaemia. Cancer Cell 30:792-805. (Preview)

Koechlein Make obvious, Harris JR, Lee T, Weeks J, Fox RG, Zimdahl All thumbs, Ito T, Blevins A, Psychologist S-H, Chute JP, Chourasia Well-organized, Covert M and Reya T. 2016.

High-resolution imaging and computational analysis eliminate haematopoietic cell dynamics in vivo. Nature Communications 7:12169. doi: 10.1038/ncomms12169.

Fox R, Lytle N, Jaquish Recycle, Park F, Ito T, Bajaj J, Koechlein C, Zimdahl Uneasy, Yano M, Kopp J, Kritzik M, Sicklick J, Sander Classification, Grandgenett PM, Hollingsworth MA, Shibata S, Pizzo D, Valasek Category, Sasik R, Scadeng M, Okano H, Kim Y, MacLeod Distinction, Lowy A and Reya T. 2016.

Thoughts based identification and targeting wages cancer stem cells in pancreatic adenocarcinoma. Nature 534:407-411.